Accuracy in Pharmaceuticals

Accuracy:

     Accuracy defines the agreement between the true value and the value found in the testing. The closeness of the result obtained during measurement or analysis to the true value. Bias is a systematic deviation from the true value. It normally refers to the difference between the mean of the set of results of analysis of the unknown are compared with the results obtained from the analysis of standards or reference materials. Accuracy expresses closeness of agreement between the value which is accepted either as a conventional true value or an accepted reference value and the value found. Accuracy can be determined by comparing the results with those obtained using an alternative method which has already been validated. Accuracy may be determined by applying the procedure to samples of the material to be examined that have been prepared with quantitative accuracy. For analytical methods there are two possible ways of determining the accuracy; the so- called absolute method and the comparative method.