Sunday, October 27, 2013

Binding Agent

Binding Agent


Binder:
 Binders are adhesive materials used to hold powders together as granules & to assist in ultimately holding the compressed tablet together.
Binder is of two types:


-         Solution binder
-         Dry binder.
Solution Binders :
 
-         Starch paste (10-17%)
-         Gelatin solution (10-20%)
-         Sucrose syrup (50-85%)
-         Glucose solution (50% alcohol, 25% glucose and 25% water)
-         Methyl cellulose 4% in alcohol.
-         Ethyl cellulose 5% in alcohol.
-         Starch- acacia paste( starch 5%, acacia 2% in water)
-         Sodium CMC.
-         PVP in aqueous, alcoholic and hydro alcoholic soln
-         Polyethylene glycol.
Dry Binder:
 
-         Cellulose
-         Methyl cellulose
-         PVP
-         Polyethylene Glycol.

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