Dissolution
Dissolution:
The process by which the solid particle or medicament are
dissolve in suitable solvent for ease of absorption.
Difference between Dissolution and assay?
Dissolution is the amount of drug released in a certain
period of time from a dosage form on the other hand Assay is the amount of drug
that is contained by a unit dosage form of medicament. The amount of drug that
is contained by a unit dosage form of medicament may not be released completely
after a certain period of time.
Why it is important character of a tablet & capsule?
Tablet & Capsule are solid dosage form. Unless
dissolve the content of the Tablet or Capsule in a suitable solvent it cannot
be reached in the systemic circulation by absorption. For this reason
dissolution is important character of Tablet & Capsule that is solid dosage
form. Simulated Gastric Fluid (SGF) & Simulated Gastro Intestinal Fluid
(SIGF) are widely used as dissolution media.
The dissolution media of tablet and capsule? Why it is different?
The commonly used dissolution media of tablet &
capsule are Simulated Gastric Fluid (SGF) & Simulated Gastro Intestinal
Fluid (SIGF). They are deferent because some drug are dissolve in Gastric pH
and some drug are dissolve in intestinal pH.
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